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Tumor perfusion imaging with 62Cu-ETS
January 2015 Update New published study demonstrates the feasibility of whole-body (62)Cu-ethylglyoxal bis(thiosemicarbazonato)copper(II) ((62)Cu-ETS) PET/CT tumor perfusion imaging in patients with metastatic renal carcinoma:
Fletcher JW, Logan TF, Eitel JA, Mathias CJ, Ng Y, et al. Whole-body PET/CT evaluation of tumor perfusion using generator-based 62Cu-ethylglyoxal bis(thiosemicarbazonato)copper(II): validation by direct comparison to 15O-water in metastatic renal cell carcinoma. J Nucl Med, 2015; 56(1):56-62. [Pubmed]
See list of publications under Resources/Publications for more.
Proportional Technologies, Inc. (PTI) is introducing a line of neutron detection products based on its patented boron-coated straw (BCS) detector (U.S. Patent 7,002,159). The BCS is a low-cost, reliable technology that converts neutrons in boron (B-10), a material that is high in natural abundance, and has easy, economical isotopic separation methodology.
- Intrinsically insensitive to gamma radiation; requires no signal processing to reject gammas
- Achieves >70% intrinsic efficiency, higher than any other technology
- Very long 30-year lifetime (99%) estimated from rigorous ALT. No scintillators or photomultipliers, known to have lifetime issues
- Advantages over competing technologies (follow link for an overview)
The BCS is an excellent alternative to 3He-based detectors in large-scale / wide-deployment applications, such as portal monitoring, long-range detection, and portable or handheld devices. The following products are currently available in customized configurations: